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Find out how to Use Progesterone

Earlier than you think about using progesterone, it is very important perceive that it isn’t a magic bullet, and that you just get probably the most profit by implementing a Bioenergetic weight loss plan strategy that means that you can successfully burn glucose as your major gas with out backing up electrons in your mitochondria that reduces your vitality manufacturing. My new e book, “Your Information to Mobile Well being: Unlocking the Science of Longevity and Pleasure,” covers this course of in nice element.

After you have dialed in your weight loss plan, an efficient technique that may assist counteract estrogen extra is to take transmucosal progesterone (i.e., utilized to your gums, not oral or transdermal), which is a pure estrogen antagonist. Progesterone is considered one of solely three hormones I imagine many adults can profit from. (The opposite two are DHEA and pregnenolone.)

I don’t advocate transdermal progesterone, as your pores and skin expresses excessive ranges of 5-alpha reductase enzyme, which causes a good portion of the progesterone you are taking to be irreversibly transformed primarily into allopregnanolone and can’t be transformed again into progesterone.

Perfect Strategy to Administer Progesterone

Please word that when progesterone is used transmucosally in your gums as I counsel, the FDA believes that someway converts it right into a drug and prohibits any firm from advising that on its label. This is the reason corporations promote their progesterone merchandise as “topical.”

Nonetheless, please perceive that it’s completely authorized for any doctor to advocate an off-label indication for a drug to their affected person. On this case, progesterone is a pure hormone and never a drug and may be very protected even in excessive doses. That is in contrast to artificial progesterone known as progestins which might be utilized by drug corporations, however continuously, and incorrectly, referred.

Dr. Ray Peat has accomplished the seminal work in progesterone and possibly was the world’s best professional on progesterone. He wrote his Ph.D. on estrogen in 1982 and spent most of his skilled profession documenting the necessity to counteract the risks of extra estrogen with low LA diets and transmucosal progesterone supplementation.

He decided that almost all solvents don’t dissolve progesterone properly and found that vitamin E is one of the best solvent to optimally present progesterone in your tissue. Vitamin E additionally protects you in opposition to harm from LA. You simply should be very cautious about which vitamin E you employ as most supplemental vitamin E in the marketplace is worse than nugatory and can trigger you hurt not profit.


It’s crucial to keep away from utilizing any artificial vitamin E (alpha tocopherol acetate — the acetate signifies that it is artificial). Pure vitamin E might be labeled “d alpha tocopherol.” That is the pure D isomer, which is what your physique can use.

There are additionally different vitamin E isomers, and also you need the entire spectrum of tocopherols and tocotrienols, particularly the beta, gamma, and delta sorts, within the efficient D isomer. For instance of a really perfect vitamin E, you possibly can take a look at the label on our vitamin E in our retailer. You should utilize any model that has an identical label.

You should purchase pharmaceutical grade bioidentical progesterone as Progesterone Powder, Bioidentical Micronized Powder, 10 grams for about $40 on many on-line shops like Amazon. That’s practically a 12 months’s provide, relying on the dose you select.

Nonetheless, you’ll need to buy some small stainless-steel measuring spoons as you’ll need a 1/64 tsp, which is 25 mg and a 1/32 tsp, which is 50 mg. A standard dose is often 25 to 50 mg and is taken half-hour earlier than mattress, because it has an anti-cortisol perform and can improve GABA ranges for night time’s sleep.

In case you are a menstruating girl, it is best to take the progesterone throughout the luteal part or the final half of your cycle, which could be decided by beginning 10 days after the primary day of your interval and stopping the progesterone when your interval begins.

In case you are a male or non-menstruating girl, you possibly can take the progesterone daily for 4 to 6 months after which cycle off for one week. The perfect time of day to take progesterone is half-hour earlier than mattress because it has an anti-cortisol perform and can improve GABA ranges for night time’s sleep.

That is what I’ve been personally doing for over a 12 months with excellent outcomes. I’m a doctor so should not have any issues doing this. If you happen to aren’t a doctor, it is best to seek the advice of one earlier than utilizing this remedy, as transmucosal progesterone remedy requires a physician’s prescription.

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