Semaglutide, generally recognized below the model names Ozempic and Wegovy, has taken the burden loss world by storm. And, because it helps with weight reduction, it’s good for sort 2 diabetes, as weight reduction is the first approach to reverse the signs of sort 2 diabetes. Semaglutide does cut back urge for food since you really feel fuller longer. Nevertheless, it isn’t a miracle treatment, and it comes with unwanted side effects. I’ve written beforehand about Ozempic face, weight reduction plateaus, regaining weight after you cease Ozempic, ineffectiveness for some folks, in addition to pure options and fiber-rich meals that naturally work like semaglutide, simply to a lesser diploma. However now a brand new aspect impact is rising—SIBO (small intestinal bacterial overgrowth). So, let’s take a better take a look at this.

Understanding SIBO and Its Connection to Semaglutide

SIBO happens when extreme micro organism develop within the small gut, resulting in signs like bloating, diarrhea, belly ache, and meals intolerances. A scarcity of intestine motility could also be a part of the reason for SIBO, together with a low manufacturing of hydrochloric acid within the abdomen. Ultimately, the pure defenses of the small gut are compromised, and SIBO outcomes.

The Printed Case Report of SIBO and Semaglutide

A case report revealed in Canadian Journal of Physiology and Pharmacology describes a 35-year-old male who managed to lose 50 kilos ( 22.7 kg) over 120 days on oral semaglutide. Although he had earlier lactose intolerance, it bought worse whereas taking semaglutide. And he additionally developed a brand new gluten intolerance. Then about six months after discontinuing semaglutide, he was identified with SIBO, suggesting the drug could have contributed to or made this situation worse. The truth that the meals intolerances didn’t simply go away when he stopped taking semaglutide is particularly regarding. Apparently, there was a change each within the GI tract motility and the micro organism that loved these situations that persevered after the drug was stopped.

How Semaglutide May Contribute to SIBO

Semaglutide’s important impact is slowing down the emptying of the abdomen and slowing down intestinal transit. That impact makes you’re feeling full longer for sue, but it surely additionally creates the proper atmosphere for micro organism to proliferate within the small gut. Micro organism die-off within the abdomen isn’t good, and the micro organism load could be substantial. So, even when 1 in 10,000 micro organism get via, however they get to hang around within the small gut and adapt  resistance to bile salts, then they’ll colonize the small gut and dwell off the sugars and brief chain carbohydrates that come their manner.

This case report is simply from one man, however anecdotal studies from different clinicians counsel that is removed from the one case. If you have already got sort 2 diabetes, and have any form of meals intolerances, this new aspect impact ought to provide you with pause. Do you actually need to cope with SIBO?

Semaglutide’s Aspect Impact Listing is Getting Longer

In our earlier articles about weight reduction and semaglutide, we’ve coated a number of unwanted side effects related to semaglutide. “Ozempic Face: Learn how to Lose Weight With out Trying Older” mentioned the gaunt, aged look some customers expertise because of speedy fats and muscle loss when taking semaglutide. “Learn how to Overcome a Weight Loss Plateau” explored why progress stalls for some. Within the article “Scuffling with Ozempic Not Working? Right here’s Learn how to Repair It” I talked about how Ozempic doesn’t work for everyone, and the frequent myths that folks imagine about weight reduction medication. I didn’t discuss in regards to the uncommon unwanted side effects like elevated danger of pancreatitis.

SIBO provides a complete new form of aspect impact to the checklist. Not like beauty issues about Ozempic face, or plateauing weight reduction, SIBO actually impacts your high quality of life. It’s most likely worse than the diabetes itself. You will need to no less than quickly use a low FODMAP weight loss program to handle the bloating and diarrhea. It’s a very restrictive weight loss program and doesn’t actually aid you get higher both.

For some folks, the trade-off of simple weight reduction with Ozempic for a persistent case of SIBO. I do know a couple of individuals who have struggled with SIBO for years and nonetheless haven’t overcome it. I believe coping with sort 2 diabetes is far simpler than overcoming SIBO. Attempting to vary entrenched micro organism within the intestinal tract is a troublesome proposition.

We now have a number of articles about concepts for sustainable weight reduction. You possibly can see an summary of them within the article, “The Full Information to Wholesome Weight Loss: What Works and Why.” In spite of everything, even with weigh loss medication, to achieve success long-term you need to be taught to eat wholesome meals, and get train to take care of weight reduction.

Conclusion: Is Semaglutide Definitely worth the Dangers?

Semaglutide is a robust drug for serving to folks drop pounds. But it surely has drawbacks. If you find yourself with SIBO, you may need wished that you simply had by no means taken the drug to start out with. It isn’t recognized but how prevalent the incidence of SIBO is with semaglutide use. But when you have already got meals intolerances, you most likely have a better probability of SIBO with the drug.

As talked about above, it is best to take a look at our information on sustainable weight reduction suggestions. There are options to happening a crash course with Ozempic.